On the other hand, anxiety symptoms in patients with coronary artery disease have been shown to be more effective in increased platelet activity than depression. Increased platelet activity has been detected in patients with major depression with a history of myocardial infarction and also in patients without any other risk factors effecting platelet activity. It also aggravates physical diseases especially cardiovascular disorders. Major depressive disorder is a common companion to GAD beside increased rates of alcohol and substance abuse. GAD patients are more likely to be encountered at primary health care facilities with non-specific complaints such as headache, muscle stiffness, gastrointestinal complaints, back pain and insomnia.
The lifetime prevalence is thought to be between 5.7% and 14.2%.
Generalized anxiety disorder (GAD) is characterized by persistent and chronic anxiety state that lasts for at least 6 months which takes place in multiple areas of life. We believe that further controlled prospective studies about this issue will be valuable. According to ROC curve analysis for differentiation of GAD from those in the control group, MPV would be considered to be a “poor” biochemical marker. This finding is consistent with the non-linear inverse relation between platelet volume and platelet count. Also platelet levels were found to be significantly lower in GAD patients in our study. The area under the ROC curve (AUC) of MPV levels for GAD was 0.655 (95% CI: 0.557–0.754, p < .001).ĭISCUSSION: Increased MPV levels in GAD patients in our study supports the hypothesis of increased platelet activation due to sympathetic system activation. RESULTS: MPV was found to be significantly higher ( p = .008) and platelet count was found to be significantly lower in the GAD group ( p = .001). METHOD: In this first retrospective cohort study about MPV among GAD patients, we compared complete blood count especially in terms of platelet count (PLT), platelet distribution width (PDW), plateletcrit (PCT) and MPV values of 60 GAD patients with 60 healthy controls. Mean platelet volume (MPV), which is indicative of platelet size, is accepted as an indication of platelet activity. Stressful life events and anxiety usually cause an increase in platelet volume and activity through various mechanisms. Within a few hours you will get your Platelet count and MPV Test reports by your pathologist.OBJECTIVE: Generalized anxiety disorder (GAD) is characterized by persistent and chronic anxiety state. A pathologist is a physician in the medical field who thoroughly studies the causes and effects of disease. During the Platelet count and MPV blood tests, a pathologist will put a needle into your veins and take out a small quantity of blood. If your doctor wants Platelet count and MPV tests on you, you may need to go through these tests. Motapada How the Platelet count and MPV Tests Are Done : Ukrainian Catholic Eparchy of New Westminster This page has got the maximum number of views from the below mentioned cities (traffic in last 30 days): You might also get these tests if your physician thinks you have some other disease. If you take Platelet count and MPV blood tests and the results are higher than 450 thou/uL for Platelet count and lower than 6.8 fL for MPV, your physician may recommend more tests to figure out the problem. High Platelet count and low MPV can be caused by a lot of reasons. Upload blood test report nowĬonsult a doctor for your Platelet count problem Our Platelet count expert will provide you with the most accurate interpretation of your blood test results and treatment within 12 hours. If you want your blood test report to be interpreted by Platelet count specialist, then you can upload your report. Normal range of Platelet count : 150 - 450 thou/uL Ideal values of Platelet count depending on age : Age But if your levels are lesser or greater than the above values, then there may be some problem in your body. If your Platelet count is in between 150 thou/uL and 450 thou/uL and your MPV is in between 6.8 fL and 10.9 fL then you need not worry as these are the normal ranges for Platelet count and MPV respectively. High Platelet count and low MPV can be caused by many reasons.
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